Read more about the article  Hepatitis C Virus fusion mechanism
Analytical Genomics / Article / News

 Hepatitis C Virus fusion mechanism

"A protein coevolution method uncovers critical features of the Hepatitis C Virus fusion mechanism" appeared in PLoS Pathogens, from A.Carbone team. This work sheds light on important structural features of the HCV fusion mechanism and contributes to advance our functional understanding of this process. This study also provides an important proof of concept that coevolution can be employed to explore viral protein mediated-processes, and can guide the development of innovative translational strategies against challenging human-tropic viruses.To the Article

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6 March 2018
Analytical Genomics / Publications

A protein coevolution method designed for conserved sequences uncovers critical features of the original HCV fusion mechanism and provides molecular basis for the design of effective antiviral strategies

Douam F., Fusil F., Enguehard M., Dib L., Nadalin F., Schwaller L., Hrebikova G., Mancip J., Mailly L., Montserret R., Ding Q., Maisse C., Carlot E., Xu K., Verhoeyen E., Baumert T., Ploss A., Carbone A., Cosset F., Lavillette D. PLOS Pathogens (2018)

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5 March 2018
Read more about the article Meet-U
Analytical Genomics / Meeting

Meet-U

Elodie Laine of the Analytical Genomics team co-organized the Meet-U colloquium on the 10th of January 2018: http://meet-u.org/colloquium_2018.html. Meet-U aims at bridging the gap between teaching and research in computational and quantitative biology. It brings together Sorbonne Université, Univ. Paris-Sud and Univ. Paris-Diderot.The theme of this year was protein-protein docking: http://meet-u.org/edition_2018.html. »

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10 January 2018
Read more about the article Meet-U
Analytical Genomics / News

Meet-U

Elodie Laine of the Analytical Genomics team co-organized the Meet-U colloquium on the 10th of January 2018: http://meet-u.org/colloquium_2018.html. Meet-U aims at bridging the gap between teaching and research in computational and quantitative biology. It brings together Sorbonne Université, Univ. Paris-Sud and Univ. Paris-Diderot.The theme of this year was protein-protein docking: http://meet-u.org/edition_2018.html. »

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10 January 2018