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Laboratory of Computational, Quantitative and Synthetic Biology (CQSB)

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Laboratory of Computational, Quantitative and Synthetic Biology (CQSB)
UMR 7238 CNRS - Sorbonne Université
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CNRS-grand-1200pxl-f40
  • Home
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    • Publications
    • Softwares
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  • Teams
    • Adaptation, Intégration, Reticulation, Evolution (AIRE)
    • Analytical Genomics
    • Biology of Genomes
    • Computational Medicine
    • Epigenetics and RNA Metabolism in Human Diseases
    • Functional Imaging Of Nuclear Architecture (FIONA)
    • Genetic Networks
    • Horizontal Evolution of Algal Lifestyles (HEAL)
    • Molecular Modeling and Drug Discovery (M2D2)
    • Proteome Diversification in Evolution
    • Statistical Genomics and Biological Physics
    • Synthetic and Systems Biology of Microalgae
    • Systems Engineering and Evolution Dynamics (SEED)
    • Telomere & Genome Stability
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    • Biology of Genomes
    • Computational Medicine
    • Epigenetics and RNA Metabolism in Human Diseases
    • Functional Imaging Of Nuclear Architecture (FIONA)
    • Genetic Networks
    • Horizontal Evolution of Algal Lifestyles (HEAL)
    • Molecular Modeling and Drug Discovery (M2D2)
    • Proteome Diversification in Evolution
    • Statistical Genomics and Biological Physics
    • Synthetic and Systems Biology of Microalgae
    • Systems Engineering and Evolution Dynamics (SEED)
    • Telomere & Genome Stability
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    • Adaptation, Intégration, Reticulation, Evolution (AIRE)
    • Analytical Genomics
    • Biology of Genomes
    • Computational Medicine
    • Epigenetics and RNA Metabolism in Human Diseases
    • Functional Imaging Of Nuclear Architecture (FIONA)
    • Genetic Networks
    • Horizontal Evolution of Algal Lifestyles (HEAL)
    • Molecular Modeling and Drug Discovery (M2D2)
    • Proteome Diversification in Evolution
    • Statistical Genomics and Biological Physics
    • Synthetic and Systems Biology of Microalgae
    • Systems Engineering and Evolution Dynamics (SEED)
    • Telomere & Genome Stability
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  • Teams
    • Adaptation, Intégration, Reticulation, Evolution (AIRE)
    • Analytical Genomics
    • Biology of Genomes
    • Computational Medicine
    • Epigenetics and RNA Metabolism in Human Diseases
    • Functional Imaging Of Nuclear Architecture (FIONA)
    • Genetic Networks
    • Horizontal Evolution of Algal Lifestyles (HEAL)
    • Molecular Modeling and Drug Discovery (M2D2)
    • Proteome Diversification in Evolution
    • Statistical Genomics and Biological Physics
    • Synthetic and Systems Biology of Microalgae
    • Systems Engineering and Evolution Dynamics (SEED)
    • Telomere & Genome Stability
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  • Master BIM
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Publications / Statistical Genomics and Biological Physics

Modeling Protein Evolution via Generative Inference From Monte Carlo Chains to Population Genetics

0 Comments
19 February 2026
Biology of Genomes / Computational Medicine / Publications / Statistical Genomics and Biological Physics / Uncategorized

Integrating experimental feedback improves generative models for biological sequences.

0 Comments
31 December 2025
Publications / Statistical Genomics and Biological Physics

Towards parsimonious generative modeling of RNA families

Calvanese F., Lambert C., Nghe P., Zamponi F., Weigt M. Nucleic Acids Research (2024)

Comments Off on Towards parsimonious generative modeling of RNA families
10 June 2024
Publications / Statistical Genomics and Biological Physics

Generating interacting protein sequences using domain-to-domain translation

Meynard-Piganeau B., Fabbri C., Weigt M., Pagnani A., Feinauer C. Bioinformatics (2023)

Comments Off on Generating interacting protein sequences using domain-to-domain translation
1 July 2023
Publications / Statistical Genomics and Biological Physics

Combining phylogeny and coevolution improves the inference of interaction partners among paralogous proteins

Gandarilla-Pérez C., Pinilla S., Bitbol A., Weigt M. PLOS Computational Biology (2023)

Comments Off on Combining phylogeny and coevolution improves the inference of interaction partners among paralogous proteins
30 March 2023
Publications / Statistical Genomics and Biological Physics

Machine-learning-assisted Monte Carlo fails at sampling computationally hard problems

Ciarella S., Trinquier J., Weigt M., Zamponi F. Machine Learning: Science and Technology (2023)

Comments Off on Machine-learning-assisted Monte Carlo fails at sampling computationally hard problems
1 March 2023
Publications / Statistical Genomics and Biological Physics

TULIP: A transformer-based unsupervised language model for interacting peptides and T cell receptors that generalizes to unseen epitopes

Meynard-Piganeau B., Feinauer C., Weigt M., Walczak A., Mora T. Preprint (2023)

Comments Off on TULIP: A transformer-based unsupervised language model for interacting peptides and T cell receptors that generalizes to unseen epitopes
1 January 2023
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UMR 7238 CNRS
Sorbonne Université

UMR 7238 CNRS

Sorbonne Université

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