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Laboratory of Computational, Quantitative and Synthetic Biology (CQSB)
UMR 7238 CNRS - Sorbonne Université
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    • Horizontal Evolution of Algal Lifestyles (HEAL)
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    • Functional Imaging Of Nuclear Architecture (FIONA)
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    • Horizontal Evolution of Algal Lifestyles (HEAL)
    • Molecular Modeling and Drug Discovery (M2D2)
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    • Epigenetics and RNA Metabolism in Human Diseases
    • Functional Imaging Of Nuclear Architecture (FIONA)
    • Genetic Networks
    • Horizontal Evolution of Algal Lifestyles (HEAL)
    • Molecular Modeling and Drug Discovery (M2D2)
    • Proteome Diversification in Evolution
    • Statistical Genomics and Biological Physics
    • Synthetic and Systems Biology of Microalgae
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    • Adaptation, Intégration, Reticulation, Evolution (AIRE)
    • Analytical Genomics
    • Biology of Genomes
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    • Epigenetics and RNA Metabolism in Human Diseases
    • Functional Imaging Of Nuclear Architecture (FIONA)
    • Genetic Networks
    • Horizontal Evolution of Algal Lifestyles (HEAL)
    • Molecular Modeling and Drug Discovery (M2D2)
    • Proteome Diversification in Evolution
    • Statistical Genomics and Biological Physics
    • Synthetic and Systems Biology of Microalgae
    • Systems Engineering and Evolution Dynamics (SEED)
    • Telomere & Genome Stability
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Analytical Genomics / Publications

Protein sequence-to-structure learning: Is this the end(-to-end revolution)?

Laine E., Eismann S., Elofsson A., Grudinin S. Proteins: Structure, Function, and Bioinformatics (2021)

Comments Off on Protein sequence-to-structure learning: Is this the end(-to-end revolution)?
1 December 2021
Publications / Statistical Genomics and Biological Physics

adabmDCA: adaptive Boltzmann machine learning for biological sequences

Muntoni A., Pagnani A., Weigt M., Zamponi F. BMC Bioinformatics (2021)

Comments Off on adabmDCA: adaptive Boltzmann machine learning for biological sequences
1 December 2021
Genetic Networks / Publications

Yap5 Competes With Hap4 for the Regulation of Iron Homeostasis Genes in the Human Pathogen

Delaveau T., Thiébaut A., Benchouaia M., Merhej J., Devaux F. Frontiers in Cellular and Infection Microbiology (2021)

Comments Off on Yap5 Competes With Hap4 for the Regulation of Iron Homeostasis Genes in the Human Pathogen
26 November 2021
Publications / Statistical Genomics and Biological Physics

Efficient generative modeling of protein sequences using simple autoregressive models

Trinquier J., Uguzzoni G., Pagnani A., Zamponi F., Weigt M. Nature Communications (2021)

Comments Off on Efficient generative modeling of protein sequences using simple autoregressive models
4 October 2021
Publications / Statistical Genomics and Biological Physics

Sparse generative modeling via parameter reduction of Boltzmann machines: Application to protein-sequence families

Barrat-Charlaix P., Muntoni A., Shimagaki K., Weigt M., Zamponi F. Physical Review E (2021)

Comments Off on Sparse generative modeling via parameter reduction of Boltzmann machines: Application to protein-sequence families
6 August 2021
Mathematical Modeling in Biology / Publications / Telomere & Genome Stability

Adaptation to DNA damage as a bet-hedging mechanism in a fluctuating environment

Roux P., Salort D., Xu Z. Royal Society Open Science (2021)

Comments Off on Adaptation to DNA damage as a bet-hedging mechanism in a fluctuating environment
1 August 2021
Analytical Genomics / Publications

Assessing conservation of alternative splicing with evolutionary splicing graphs.

Zea D., Laskina S., Baudin A., Richard H., Laine E. Genome Research (2021)

Comments Off on Assessing conservation of alternative splicing with evolutionary splicing graphs.
1 August 2021
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