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Laboratory of Computational, Quantitative and Synthetic Biology (CQSB)

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Laboratory of Computational, Quantitative and Synthetic Biology (CQSB)
UMR 7238 CNRS - Sorbonne Université
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  • Home
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    • Adaptation, Intégration, Reticulation, Evolution (AIRE)
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    • Epigenetics and RNA Metabolism in Human Diseases
    • Functional Imaging Of Nuclear Architecture (FIONA)
    • Genetic Networks
    • Horizontal Evolution of Algal Lifestyles (HEAL)
    • Molecular Modeling and Drug Discovery (M2D2)
    • Proteome Diversification in Evolution
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    • Functional Imaging Of Nuclear Architecture (FIONA)
    • Genetic Networks
    • Horizontal Evolution of Algal Lifestyles (HEAL)
    • Molecular Modeling and Drug Discovery (M2D2)
    • Proteome Diversification in Evolution
    • Statistical Genomics and Biological Physics
    • Synthetic and Systems Biology of Microalgae
    • Systems Engineering and Evolution Dynamics (SEED)
    • Telomere & Genome Stability
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    • Epigenetics and RNA Metabolism in Human Diseases
    • Functional Imaging Of Nuclear Architecture (FIONA)
    • Genetic Networks
    • Horizontal Evolution of Algal Lifestyles (HEAL)
    • Molecular Modeling and Drug Discovery (M2D2)
    • Proteome Diversification in Evolution
    • Statistical Genomics and Biological Physics
    • Synthetic and Systems Biology of Microalgae
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    • Adaptation, Intégration, Reticulation, Evolution (AIRE)
    • Analytical Genomics
    • Biology of Genomes
    • Computational Medicine
    • Epigenetics and RNA Metabolism in Human Diseases
    • Functional Imaging Of Nuclear Architecture (FIONA)
    • Genetic Networks
    • Horizontal Evolution of Algal Lifestyles (HEAL)
    • Molecular Modeling and Drug Discovery (M2D2)
    • Proteome Diversification in Evolution
    • Statistical Genomics and Biological Physics
    • Synthetic and Systems Biology of Microalgae
    • Systems Engineering and Evolution Dynamics (SEED)
    • Telomere & Genome Stability
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Publications / Telomere & Genome Stability

The Polo kinase Cdc5 is regulated at multiple levels in the adaptation response to telomere dysfunction.

Coutelier H., Ilioaia O., Peillet J., Hamon M., D’Amours D., Teixeira M., Xu Z. Genetics (2023)

Comments Off on The Polo kinase Cdc5 is regulated at multiple levels in the adaptation response to telomere dysfunction.
12 January 2023
Publications / Statistical Genomics and Biological Physics

TULIP: A transformer-based unsupervised language model for interacting peptides and T cell receptors that generalizes to unseen epitopes

Meynard-Piganeau B., Feinauer C., Weigt M., Walczak A., Mora T. Preprint (2023)

Comments Off on TULIP: A transformer-based unsupervised language model for interacting peptides and T cell receptors that generalizes to unseen epitopes
1 January 2023
Analytical Genomics / Publications

Soft disorder modulates the assembly path of protein complexes

Seoane B., Carbone A. PLOS Computational Biology (2022)

Comments Off on Soft disorder modulates the assembly path of protein complexes
17 November 2022
Analytical Genomics / Publications

Deep Local Analysis evaluates protein docking conformations with locally oriented cubes.

Behbahani Y., Crouzet S., Laine E., Carbone A. Bioinformatics (2022)

Comments Off on Deep Local Analysis evaluates protein docking conformations with locally oriented cubes.
30 September 2022
Analytical Genomics / Publications / Synthetic and Systems Biology of Microalgae

Crystal structure of chloroplast fructose-1,6-bisphosphate aldolase from the green alga Chlamydomonas reinhardtii

Le Moigne T., Sarti E., Nourisson A., Zaffagnini M., Carbone A., Lemaire S., Henri J. Journal of Structural Biology (2022)

Comments Off on Crystal structure of chloroplast fructose-1,6-bisphosphate aldolase from the green alga Chlamydomonas reinhardtii
1 September 2022
Publications / Statistical Genomics and Biological Physics

Structure and Function of a Dehydrating Condensation Domain in Nonribosomal Peptide Biosynthesis

Patteson J., Fortinez C., Putz A., Rodriguez-Rivas J., Bryant L., Adhikari K., Weigt M., Schmeing T., Li B. Journal of the American Chemical Society (2022)

Comments Off on Structure and Function of a Dehydrating Condensation Domain in Nonribosomal Peptide Biosynthesis
10 August 2022
Publications / Statistical Genomics and Biological Physics

Deciphering polymorphism in 61,157 Escherichia coli genomes via epistatic sequence landscapes

Vigué L., Croce G., Petitjean M., Ruppé E., Tenaillon O., Weigt M. Nature Communications (2022)

Comments Off on Deciphering polymorphism in 61,157 Escherichia coli genomes via epistatic sequence landscapes
12 July 2022
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