Skip to content
Zamponi F – CQSB
Laboratory of Computational, Quantitative and Synthetic Biology (CQSB)

UMR 7238 CNRS - Sorbonne Universite

  • Home
  • Research
    • Publications
    • Softwares
    • Projects
    • All Teams
    • Alumni

    Teams

    • Adaptation, Intégration, Reticulation, Evolution (AIRE)
    • Analytical Genomics
    • Biology of Genomes
    • Computational Medicine
    • Epigenetics and RNA Metabolism in Human Diseases
    • Functional Imaging Of Nuclear Architecture (FIONA)
    • Genetic Networks
    • Horizontal Evolution of Algal Lifestyles (HEAL)
    • Molecular Modeling and Drug Discovery (M2D2)
    • Proteome Diversification in Evolution
    • Statistical Genomics and Biological Physics
    • Synthetic and Systems Biology of Microalgae
    • Systems Engineering and Evolution Dynamics (SEED)
    • Telomere & Genome Stability
  • Events
    • All News
    • Seminars
    • Meetings
  • Master BIM
  • Open Positions
  • Home
  • Research
    • Publications
    • Softwares
    • Projects
    • All Teams
    • Alumni

    Teams

    • Adaptation, Intégration, Reticulation, Evolution (AIRE)
    • Analytical Genomics
    • Biology of Genomes
    • Computational Medicine
    • Epigenetics and RNA Metabolism in Human Diseases
    • Functional Imaging Of Nuclear Architecture (FIONA)
    • Genetic Networks
    • Horizontal Evolution of Algal Lifestyles (HEAL)
    • Molecular Modeling and Drug Discovery (M2D2)
    • Proteome Diversification in Evolution
    • Statistical Genomics and Biological Physics
    • Synthetic and Systems Biology of Microalgae
    • Systems Engineering and Evolution Dynamics (SEED)
    • Telomere & Genome Stability
  • Events
    • All News
    • Seminars
    • Meetings
  • Master BIM
  • Open Positions
CNRS-grand-1200pxl-f40
Laboratory of Computational, Quantitative and Synthetic Biology (CQSB)
UMR 7238 CNRS - Sorbonne Université
logo
CNRS-grand-1200pxl-f40
  • Home
  • Research
    • Publications
    • Softwares
    • Projects
    • All Teams
    • Alumni
  • Teams
    • Adaptation, Intégration, Reticulation, Evolution (AIRE)
    • Analytical Genomics
    • Biology of Genomes
    • Computational Medicine
    • Epigenetics and RNA Metabolism in Human Diseases
    • Functional Imaging Of Nuclear Architecture (FIONA)
    • Genetic Networks
    • Horizontal Evolution of Algal Lifestyles (HEAL)
    • Molecular Modeling and Drug Discovery (M2D2)
    • Proteome Diversification in Evolution
    • Statistical Genomics and Biological Physics
    • Synthetic and Systems Biology of Microalgae
    • Systems Engineering and Evolution Dynamics (SEED)
    • Telomere & Genome Stability
  • Events
    • All News
    • Seminars
    • Meeting
  • Master BIM
  • Open positions
  • Home
  • Research
    • Publications
    • Softwares
    • Projects
    • All Teams
    • Alumni
  • Teams
    • Adaptation, Intégration, Reticulation, Evolution (AIRE)
    • Analytical Genomics
    • Biology of Genomes
    • Computational Medicine
    • Epigenetics and RNA Metabolism in Human Diseases
    • Functional Imaging Of Nuclear Architecture (FIONA)
    • Genetic Networks
    • Horizontal Evolution of Algal Lifestyles (HEAL)
    • Molecular Modeling and Drug Discovery (M2D2)
    • Proteome Diversification in Evolution
    • Statistical Genomics and Biological Physics
    • Synthetic and Systems Biology of Microalgae
    • Systems Engineering and Evolution Dynamics (SEED)
    • Telomere & Genome Stability
  • Events
    • All News
    • Seminars
    • Meeting
  • Master BIM
  • Open positions
logo
CNRS-grand-1200pxl-f40
  • Home
  • Research
    • Publications
    • Softwares
    • Projects
    • All Teams
    • Alumni
  • Teams
    • Adaptation, Intégration, Reticulation, Evolution (AIRE)
    • Analytical Genomics
    • Biology of Genomes
    • Computational Medicine
    • Epigenetics and RNA Metabolism in Human Diseases
    • Functional Imaging Of Nuclear Architecture (FIONA)
    • Genetic Networks
    • Horizontal Evolution of Algal Lifestyles (HEAL)
    • Molecular Modeling and Drug Discovery (M2D2)
    • Proteome Diversification in Evolution
    • Statistical Genomics and Biological Physics
    • Synthetic and Systems Biology of Microalgae
    • Systems Engineering and Evolution Dynamics (SEED)
    • Telomere & Genome Stability
  • Events
    • All News
    • Seminars
    • Meeting
  • Master BIM
  • Open positions
  • Home
  • Research
    • Publications
    • Softwares
    • Projects
    • All Teams
    • Alumni
  • Teams
    • Adaptation, Intégration, Reticulation, Evolution (AIRE)
    • Analytical Genomics
    • Biology of Genomes
    • Computational Medicine
    • Epigenetics and RNA Metabolism in Human Diseases
    • Functional Imaging Of Nuclear Architecture (FIONA)
    • Genetic Networks
    • Horizontal Evolution of Algal Lifestyles (HEAL)
    • Molecular Modeling and Drug Discovery (M2D2)
    • Proteome Diversification in Evolution
    • Statistical Genomics and Biological Physics
    • Synthetic and Systems Biology of Microalgae
    • Systems Engineering and Evolution Dynamics (SEED)
    • Telomere & Genome Stability
  • Events
    • All News
    • Seminars
    • Meeting
  • Master BIM
  • Open positions
Publications / Statistical Genomics and Biological Physics

Towards parsimonious generative modeling of RNA families

Calvanese F., Lambert C., Nghe P., Zamponi F., Weigt M. Nucleic Acids Research (2024)

Comments Off on Towards parsimonious generative modeling of RNA families
10 June 2024
Publications / Statistical Genomics and Biological Physics

Machine-learning-assisted Monte Carlo fails at sampling computationally hard problems

Ciarella S., Trinquier J., Weigt M., Zamponi F. Machine Learning: Science and Technology (2023)

Comments Off on Machine-learning-assisted Monte Carlo fails at sampling computationally hard problems
1 March 2023
Publications / Statistical Genomics and Biological Physics

Modeling Sequence-Space Exploration and Emergence of Epistatic Signals in Protein Evolution

Bisardi M., Rodriguez-Rivas J., Zamponi F., Weigt M. Molecular Biology and Evolution (2022)

Comments Off on Modeling Sequence-Space Exploration and Emergence of Epistatic Signals in Protein Evolution
7 January 2022
Publications / Statistical Genomics and Biological Physics

adabmDCA: adaptive Boltzmann machine learning for biological sequences

Muntoni A., Pagnani A., Weigt M., Zamponi F. BMC Bioinformatics (2021)

Comments Off on adabmDCA: adaptive Boltzmann machine learning for biological sequences
1 December 2021
Publications / Statistical Genomics and Biological Physics

Efficient generative modeling of protein sequences using simple autoregressive models

Trinquier J., Uguzzoni G., Pagnani A., Zamponi F., Weigt M. Nature Communications (2021)

Comments Off on Efficient generative modeling of protein sequences using simple autoregressive models
4 October 2021
Publications / Statistical Genomics and Biological Physics

Sparse generative modeling via parameter reduction of Boltzmann machines: Application to protein-sequence families

Barrat-Charlaix P., Muntoni A., Shimagaki K., Weigt M., Zamponi F. Physical Review E (2021)

Comments Off on Sparse generative modeling via parameter reduction of Boltzmann machines: Application to protein-sequence families
6 August 2021
Publications / Statistical Genomics and Biological Physics

Aligning biological sequences by exploiting residue conservation and coevolution

Muntoni A., Pagnani A., Weigt M., Zamponi F. Physical Review E (2020)

Comments Off on Aligning biological sequences by exploiting residue conservation and coevolution
7 December 2020
single-logo-CQSB-numeric-web
single-logo-CQSB-numeric-web

UMR 7238 CNRS
Sorbonne Université

UMR 7238 CNRS

Sorbonne Université

logo
logocnrs
X-twitter Youtube

© Copyright 2026 – CQSB

Contact
Legal notice
Privacy policy
Intranet
My account
Help

Contact
Legal notice
Privacy policy
Intranet
My account
Help

X-twitter Youtube

© Copyright 2026 – CQSB

Search this website Type then hit enter to search Press Escape to close the search panel.

⚙️ Site en cours de recette technique
Version de démonstration — certaines fonctionnalités peuvent être incomplètes.

⚙️ Website under technical review
Demo version — some features may be incomplete or temporarily unavailable.