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Laboratory of Computational, Quantitative and Synthetic Biology (CQSB)
UMR 7238 CNRS - Sorbonne Université
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CNRS-grand-1200pxl-f40
  • Home
  • Research
    • Publications
    • Softwares
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  • Teams
    • Adaptation, Intégration, Reticulation, Evolution (AIRE)
    • Analytical Genomics
    • Biology of Genomes
    • Computational Medicine
    • Epigenetics and RNA Metabolism in Human Diseases
    • Functional Imaging Of Nuclear Architecture (FIONA)
    • Genetic Networks
    • Horizontal Evolution of Algal Lifestyles (HEAL)
    • Molecular Modeling and Drug Discovery (M2D2)
    • Proteome Diversification in Evolution
    • Statistical Genomics and Biological Physics
    • Synthetic and Systems Biology of Microalgae
    • Systems Engineering and Evolution Dynamics (SEED)
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    • Computational Medicine
    • Epigenetics and RNA Metabolism in Human Diseases
    • Functional Imaging Of Nuclear Architecture (FIONA)
    • Genetic Networks
    • Horizontal Evolution of Algal Lifestyles (HEAL)
    • Molecular Modeling and Drug Discovery (M2D2)
    • Proteome Diversification in Evolution
    • Statistical Genomics and Biological Physics
    • Synthetic and Systems Biology of Microalgae
    • Systems Engineering and Evolution Dynamics (SEED)
    • Telomere & Genome Stability
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  • Home
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    • Adaptation, Intégration, Reticulation, Evolution (AIRE)
    • Analytical Genomics
    • Biology of Genomes
    • Computational Medicine
    • Epigenetics and RNA Metabolism in Human Diseases
    • Functional Imaging Of Nuclear Architecture (FIONA)
    • Genetic Networks
    • Horizontal Evolution of Algal Lifestyles (HEAL)
    • Molecular Modeling and Drug Discovery (M2D2)
    • Proteome Diversification in Evolution
    • Statistical Genomics and Biological Physics
    • Synthetic and Systems Biology of Microalgae
    • Systems Engineering and Evolution Dynamics (SEED)
    • Telomere & Genome Stability
  • Events
    • All News
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  • Master BIM
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  • Home
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    • Publications
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    • All Teams
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  • Teams
    • Adaptation, Intégration, Reticulation, Evolution (AIRE)
    • Analytical Genomics
    • Biology of Genomes
    • Computational Medicine
    • Epigenetics and RNA Metabolism in Human Diseases
    • Functional Imaging Of Nuclear Architecture (FIONA)
    • Genetic Networks
    • Horizontal Evolution of Algal Lifestyles (HEAL)
    • Molecular Modeling and Drug Discovery (M2D2)
    • Proteome Diversification in Evolution
    • Statistical Genomics and Biological Physics
    • Synthetic and Systems Biology of Microalgae
    • Systems Engineering and Evolution Dynamics (SEED)
    • Telomere & Genome Stability
  • Events
    • All News
    • Seminars
    • Meeting
  • Master BIM
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Analytical Genomics / Publications

Predicting Protein Functional Motions: an Old Recipe with a New Twist

Grudinin S., Laine E., Hoffmann A. Biophysical Journal (2020)

Comments Off on Predicting Protein Functional Motions: an Old Recipe with a New Twist
1 May 2020
Analytical Genomics / Publications

Transcripts’ Evolutionary History and Structural Dynamics Give Mechanistic Insights into the Functional Diversity of the JNK Family

Ait-hamlat A., Zea D., Labeeuw A., Polit L., Richard H., Laine E. Journal of Molecular Biology (2020)

Comments Off on Transcripts’ Evolutionary History and Structural Dynamics Give Mechanistic Insights into the Functional Diversity of the JNK Family
1 March 2020
Analytical Genomics / Publications

Multiple protein-DNA interfaces unravelled by evolutionary information, physico-chemical and geometrical properties

Corsi F., Lavery R., Laine E., Carbone A. PLOS Computational Biology (2020)

Comments Off on Multiple protein-DNA interfaces unravelled by evolutionary information, physico-chemical and geometrical properties
3 February 2020
Analytical Genomics / Publications

GEMME: A Simple and Fast Global Epistatic Model Predicting Mutational Effects

Laine E., Karami Y., Carbone A. Molecular Biology and Evolution (2019)

Comments Off on GEMME: A Simple and Fast Global Epistatic Model Predicting Mutational Effects
1 November 2019
Analytical Genomics / Publications

Decrypting protein surfaces by combining evolution, geometry and molecular docking

Dequeker C., Laine E., Carbone A. Proteins: Structure, Function, and Bioinformatics (2019)

Comments Off on Decrypting protein surfaces by combining evolution, geometry and molecular docking
1 November 2019
Analytical Genomics / Publications

Multiple probabilistic models extract features from protein sequence data and resolve functional diversity of very different protein families

Vicedomini R., Bouly J., Laine E., Falciatore A., Carbone A. Preprint (2019)

Comments Off on Multiple probabilistic models extract features from protein sequence data and resolve functional diversity of very different protein families
1 January 2019
Analytical Genomics / Publications

“Infostery” analysis of short molecular dynamics simulations identifies highly sensitive residues and predicts deleterious mutations

Karami Y., Bitard-Feildel T., Laine E., Carbone A. Scientific Reports (2018)

Comments Off on “Infostery” analysis of short molecular dynamics simulations identifies highly sensitive residues and predicts deleterious mutations
31 October 2018
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UMR 7238 CNRS
Sorbonne Université

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