Softwares

Coevolution in OVerlapped sequences by Tree analysis (COVTree) is a web server providing the online analysis of coevolving amino-acid pairs in overlapping genes, where residues might be located inside or outside the overlapping region.

A method to identify highly sensitive residues and predicts deleterious mutations.

Co-evolution analysis of the envelope glycoproteins E1 and E2 of the Hepatitis C Virus (HCV) 

An empirical scoring function that estimates the binding affinity between two proteins, given the 3D structure of their complex.